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Drug interactions

Alteplase + Piroxicam

Severity: Major

Alteplase and Piroxicam: major interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Alteplase dissolves clots and NSAIDs inhibit platelet function and can injure the gastric mucosa, so bleeding risk is increased when they are combined.

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