Drug interactions
Aluminum hydroxide + Atenolol-chlorthalidone
Severity: Minor
Aluminum hydroxide and Atenolol-chlorthalidone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Aluminum-containing antacids can reduce oral absorption of atenolol, lowering its blood pressure and heart rate effects. The effect is variable and usually modest.
What this interaction means in plain words
Aluminum hydroxide and Atenolol-chlorthalidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Aluminum hydroxide belongs to Gastrointestinal Tract; Atenolol-chlorthalidone belongs to Cardiovascular.
Why it happens
Aluminum hydroxide reduces gastrointestinal absorption of atenolol, probably by binding or altered gastric conditions.
What to do
Give atenolol at least 2 hours before the antacid, and monitor heart rate and blood pressure.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Atenolol-chlorthalidone
Other interactions of Aluminum hydroxide
Frequently asked questions
Can I take Aluminum hydroxide with Atenolol-chlorthalidone?
MediHelp rates the interaction as minor. Aluminum hydroxide and Atenolol-chlorthalidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Aluminum-containing antacids can reduce oral absorption of atenolol, lowering its blood pressure and heart rate effects. The effect is variable and usually modest.
How serious is the interaction between Aluminum hydroxide and Atenolol-chlorthalidone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give atenolol at least 2 hours before the antacid, and monitor heart rate and blood pressure.
What other medicines interact with Atenolol-chlorthalidone?
MediHelp also lists interactions of Atenolol-chlorthalidone with, for example, Acebutolol, Aldesleukin. The full list is on the Atenolol-chlorthalidone page.
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