Drug interactions
Aluminum hydroxide + Baloxavir marboxil
Severity: Moderate
Aluminum hydroxide and Baloxavir marboxil: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Baloxavir can bind polyvalent cations such as aluminum in the gut. This may reduce its absorption and antiviral effect.
What this interaction means in plain words
Aluminum hydroxide and Baloxavir marboxil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Aluminum hydroxide belongs to Gastrointestinal Tract; Baloxavir marboxil belongs to Anti Virals.
Why it happens
Chelation of baloxavir by aluminum in the gastrointestinal tract reduces absorption.
What to do
Avoid taking baloxavir with aluminum-containing antacids; separate administration by at least 2 hours or choose a non-cation antacid.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Aluminum hydroxide
Frequently asked questions
Can I take Aluminum hydroxide with Baloxavir marboxil?
MediHelp rates the interaction as moderate. Aluminum hydroxide and Baloxavir marboxil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Baloxavir can bind polyvalent cations such as aluminum in the gut. This may reduce its absorption and antiviral effect.
How serious is the interaction between Aluminum hydroxide and Baloxavir marboxil?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid taking baloxavir with aluminum-containing antacids; separate administration by at least 2 hours or choose a non-cation antacid.
What other medicines interact with Aluminum hydroxide?
MediHelp also lists interactions of Aluminum hydroxide with, for example, Ciprofloxacin, Deferasirox, Dolutegravir. The full list is on the Aluminum hydroxide page.
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