Drug interactions
Aluminum hydroxide + Cefditoren
Severity: Moderate
Aluminum hydroxide and Cefditoren: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Aluminum- and magnesium-containing antacids reduce cefditoren pivoxil absorption, which may lead to lower antibacterial exposure. Acid suppression has a similar effect.
What this interaction means in plain words
Aluminum hydroxide and Cefditoren can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Aluminum hydroxide belongs to Gastrointestinal Tract; Cefditoren belongs to Anti Bacterial.
Why it happens
Increased gastric pH reduces absorption of cefditoren pivoxil.
What to do
Avoid concurrent use or give cefditoren at least 2 hours apart from antacids. Monitor clinical response to the antibiotic.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Aluminum hydroxide
Frequently asked questions
Can I take Aluminum hydroxide with Cefditoren?
MediHelp rates the interaction as moderate. Aluminum hydroxide and Cefditoren can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Aluminum- and magnesium-containing antacids reduce cefditoren pivoxil absorption, which may lead to lower antibacterial exposure. Acid suppression has a similar effect.
How serious is the interaction between Aluminum hydroxide and Cefditoren?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use or give cefditoren at least 2 hours apart from antacids. Monitor clinical response to the antibiotic.
What other medicines interact with Aluminum hydroxide?
MediHelp also lists interactions of Aluminum hydroxide with, for example, Ciprofloxacin, Deferasirox, Dolutegravir. The full list is on the Aluminum hydroxide page.
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