Drug interactions
Aluminum hydroxide + Chenodiol
Severity: Moderate
Aluminum hydroxide and Chenodiol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Aluminum-based antacids can adsorb bile acids, lowering chenodiol absorption and efficacy in gallstone dissolution.
What this interaction means in plain words
Aluminum hydroxide and Chenodiol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Aluminum hydroxide belongs to Gastrointestinal Tract; Chenodiol belongs to Gastrointestinal Tract.
Why it happens
Aluminum hydroxide binds bile acids in the gut, reducing chenodiol absorption.
What to do
Avoid aluminum-containing antacids or separate by at least 2 hours. Monitor therapeutic response.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Aluminum hydroxide
Frequently asked questions
Can I take Aluminum hydroxide with Chenodiol?
MediHelp rates the interaction as moderate. Aluminum hydroxide and Chenodiol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Aluminum-based antacids can adsorb bile acids, lowering chenodiol absorption and efficacy in gallstone dissolution.
How serious is the interaction between Aluminum hydroxide and Chenodiol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid aluminum-containing antacids or separate by at least 2 hours. Monitor therapeutic response.
What other medicines interact with Aluminum hydroxide?
MediHelp also lists interactions of Aluminum hydroxide with, for example, Ciprofloxacin, Deferasirox, Dolutegravir. The full list is on the Aluminum hydroxide page.
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