Drug interactions
Aluminum hydroxide + Cyclosporine
Severity: Moderate
Aluminum hydroxide and Cyclosporine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Antacids may reduce cyclosporine absorption, though data are limited and inconsistent. A drop in levels could risk rejection in transplant patients.
What this interaction means in plain words
Aluminum hydroxide and Cyclosporine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Possible reduced GI absorption through binding or pH changes.
What to do
Separate doses by at least 2 hours and monitor cyclosporine trough levels when antacid use starts or stops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Aluminum hydroxide
Frequently asked questions
Can I take Aluminum hydroxide with Cyclosporine?
MediHelp rates the interaction as moderate. Aluminum hydroxide and Cyclosporine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Antacids may reduce cyclosporine absorption, though data are limited and inconsistent. A drop in levels could risk rejection in transplant patients.
How serious is the interaction between Aluminum hydroxide and Cyclosporine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate doses by at least 2 hours and monitor cyclosporine trough levels when antacid use starts or stops.
What other medicines interact with Aluminum hydroxide?
MediHelp also lists interactions of Aluminum hydroxide with, for example, Ciprofloxacin, Deferasirox, Dolutegravir. The full list is on the Aluminum hydroxide page.
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