Skip to content

Drug interactions

Aluminum hydroxide + Erythromycin base

Severity: Minor

Aluminum hydroxide and Erythromycin base: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

An increase in erythromycin levels with aluminum antacids has been suggested, but the data are weak. Any effect is likely small and of little clinical importance.

What this interaction means in plain words

Aluminum hydroxide and Erythromycin base have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Mechanism is not established.

What to do

No change is needed. Monitor for GI intolerance or QT-related symptoms if other risk factors are present.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ members

Unlock the full page

Create an account and start a Pro+ trial to see why Aluminum hydroxide and Erythromycin base interact, what to do about it, and the sources.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Try Pro+ free for 14 days on the web. No card needed.

Frequently asked questions

Can I take Aluminum hydroxide with Erythromycin base?

MediHelp rates the interaction as minor. Aluminum hydroxide and Erythromycin base have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. An increase in erythromycin levels with aluminum antacids has been suggested, but the data are weak. Any effect is likely small and of little clinical importance.

How serious is the interaction between Aluminum hydroxide and Erythromycin base?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No change is needed. Monitor for GI intolerance or QT-related symptoms if other risk factors are present.

What other medicines interact with Aluminum hydroxide?

MediHelp also lists interactions of Aluminum hydroxide with, for example, Ciprofloxacin, Deferasirox, Dolutegravir. The full list is on the Aluminum hydroxide page.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

Browse A–Z · Drug interactions

Get the app Sign in