Drug interactions
Aluminum hydroxide + Erythromycin
Severity: Minor
Aluminum hydroxide and Erythromycin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Antacids containing aluminum may slightly change erythromycin absorption, but the effect is small and inconsistent. It is generally not clinically important.
What this interaction means in plain words
Aluminum hydroxide and Erythromycin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Aluminum hydroxide belongs to Gastrointestinal Tract; Erythromycin belongs to Anti Bacterial.
Why it happens
Possible minor alteration of gastric pH or binding affecting absorption; mechanism not firmly established.
What to do
No dose change is needed; separating doses by about two hours is a reasonable precaution.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Aluminum hydroxide
Frequently asked questions
Can I take Aluminum hydroxide with Erythromycin?
MediHelp rates the interaction as minor. Aluminum hydroxide and Erythromycin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Antacids containing aluminum may slightly change erythromycin absorption, but the effect is small and inconsistent. It is generally not clinically important.
How serious is the interaction between Aluminum hydroxide and Erythromycin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is needed; separating doses by about two hours is a reasonable precaution.
What other medicines interact with Aluminum hydroxide?
MediHelp also lists interactions of Aluminum hydroxide with, for example, Ciprofloxacin, Deferasirox, Dolutegravir. The full list is on the Aluminum hydroxide page.
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