Drug interactions
Aluminum hydroxide + Penbutolol
Severity: Minor
Aluminum hydroxide and Penbutolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Aluminum-containing antacids have lowered the absorption of some beta-blockers. The result can be a reduced blood pressure or heart rate effect.
What this interaction means in plain words
Aluminum hydroxide and Penbutolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Adsorption or binding in the gut reduces beta-blocker absorption.
What to do
Separate doses by about 2 hours. Monitor blood pressure and heart rate.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Aluminum hydroxide
Frequently asked questions
Can I take Aluminum hydroxide with Penbutolol?
MediHelp rates the interaction as minor. Aluminum hydroxide and Penbutolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Aluminum-containing antacids have lowered the absorption of some beta-blockers. The result can be a reduced blood pressure or heart rate effect.
How serious is the interaction between Aluminum hydroxide and Penbutolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate doses by about 2 hours. Monitor blood pressure and heart rate.
What other medicines interact with Aluminum hydroxide?
MediHelp also lists interactions of Aluminum hydroxide with, for example, Ciprofloxacin, Deferasirox, Dolutegravir. The full list is on the Aluminum hydroxide page.
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