Drug interactions
Aluminum hydroxide + Perindopril
Severity: Minor
Aluminum hydroxide and Perindopril: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Antacids may modestly reduce the absorption of some ACE inhibitors. Any loss of blood pressure control is likely small.
What this interaction means in plain words
Aluminum hydroxide and Perindopril have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Aluminum hydroxide belongs to Gastrointestinal Tract; Perindopril belongs to Cardiovascular.
Why it happens
Antacid components may reduce gastrointestinal absorption of the ACE inhibitor; the mechanism is not firmly established.
What to do
Separate doses by about 2 hours. Monitor blood pressure if antacids are used regularly.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Aluminum hydroxide
Other interactions of Perindopril
- Aliskiren + Perindopril Contraindicated
- Amifostine + Perindopril Major
- Amiloride + Perindopril Major
Frequently asked questions
Can I take Aluminum hydroxide with Perindopril?
MediHelp rates the interaction as minor. Aluminum hydroxide and Perindopril have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Antacids may modestly reduce the absorption of some ACE inhibitors. Any loss of blood pressure control is likely small.
How serious is the interaction between Aluminum hydroxide and Perindopril?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate doses by about 2 hours. Monitor blood pressure if antacids are used regularly.
What other medicines interact with Aluminum hydroxide?
MediHelp also lists interactions of Aluminum hydroxide with, for example, Ciprofloxacin, Deferasirox, Dolutegravir. The full list is on the Aluminum hydroxide page.
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