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Drug interactions

Aluminum hydroxide + Propranolol

Severity: Minor

Aluminum hydroxide and Propranolol: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Aluminum hydroxide has been reported to reduce propranolol absorption and lower its plasma levels. The result may be a slight loss of heart rate and blood pressure control.

What this interaction means in plain words

Aluminum hydroxide and Propranolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Aluminum hydroxide belongs to Gastrointestinal Tract; Propranolol belongs to Cardiovascular.

Evidence level: Moderate

Why it happens

Adsorption or binding in the gut lumen reduces propranolol absorption.

What to do

Give propranolol at least 2 hours apart from the antacid. Monitor heart rate and blood pressure if the antacid is used regularly.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Aluminum hydroxide with Propranolol?

MediHelp rates the interaction as minor. Aluminum hydroxide and Propranolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Aluminum hydroxide has been reported to reduce propranolol absorption and lower its plasma levels. The result may be a slight loss of heart rate and blood pressure control.

How serious is the interaction between Aluminum hydroxide and Propranolol?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give propranolol at least 2 hours apart from the antacid. Monitor heart rate and blood pressure if the antacid is used regularly.

What other medicines interact with Aluminum hydroxide?

MediHelp also lists interactions of Aluminum hydroxide with, for example, Ciprofloxacin, Deferasirox, Dolutegravir. The full list is on the Aluminum hydroxide page.

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