Drug interactions
Aluminum hydroxide + Trandolapril
Severity: Minor
Aluminum hydroxide and Trandolapril: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Antacids may slightly reduce the absorption of ACE inhibitors. Any effect on blood pressure is likely small.
What this interaction means in plain words
Aluminum hydroxide and Trandolapril have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Aluminum hydroxide belongs to Gastrointestinal Tract; Trandolapril belongs to Cardiovascular.
Why it happens
Antacid components may reduce gastrointestinal absorption of the ACE inhibitor; the mechanism is not firmly established.
What to do
Separate doses by about 2 hours. Monitor blood pressure if antacids are used regularly.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to see why Aluminum hydroxide and Trandolapril interact, what to do about it, and the sources.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Aluminum hydroxide
Other interactions of Trandolapril
- Aliskiren + Trandolapril Contraindicated
- Aldesleukin + Trandolapril Major
- Amifostine + Trandolapril Major
Frequently asked questions
Can I take Aluminum hydroxide with Trandolapril?
MediHelp rates the interaction as minor. Aluminum hydroxide and Trandolapril have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Antacids may slightly reduce the absorption of ACE inhibitors. Any effect on blood pressure is likely small.
How serious is the interaction between Aluminum hydroxide and Trandolapril?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate doses by about 2 hours. Monitor blood pressure if antacids are used regularly.
What other medicines interact with Aluminum hydroxide?
MediHelp also lists interactions of Aluminum hydroxide with, for example, Ciprofloxacin, Deferasirox, Dolutegravir. The full list is on the Aluminum hydroxide page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
