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Drug interactions

Alvimopan + Meperidine

Severity: Contraindicated

Alvimopan and Meperidine: contraindicated interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Alvimopan blocks peripheral mu-opioid receptors in the gut, and patients who have received opioids for more than 7 consecutive days are more sensitive to it.

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