Drug interactions
meperidine + phenelzine
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
Potentially fatal reactions; contraindicated.
Mechanism of action
MAOI + serotonergic opioid.
Clinical management
Contraindicated.
Drug reference
References
Frequently asked questions
Can I take meperidine with phenelzine?
The interaction is rated: Contraindicated. Potentially fatal reactions; contraindicated.
How serious is the interaction between meperidine and phenelzine?
The interaction is rated: Contraindicated. Evidence level: High.
How is the interaction between meperidine and phenelzine managed?
Contraindicated.
Why do meperidine and phenelzine interact?
MAOI + serotonergic opioid.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.