Drug interactions
Amiloride + Magnesium
Severity: Minor
Amiloride and Magnesium: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Amiloride reduces urinary magnesium loss and may raise serum magnesium slightly. This is generally beneficial, but accumulation could occur with magnesium supplements in renal impairment.
What this interaction means in plain words
Amiloride and Magnesium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amiloride belongs to Cardiovascular; Magnesium belongs to Gastrointestinal Tract.
Why it happens
Amiloride blocks distal sodium channels, reducing renal magnesium excretion.
What to do
No action is usually needed. Monitor magnesium in patients with renal impairment taking magnesium supplements.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Magnesium
- Ciprofloxacin + Magnesium Major
- Magnesium + Pancuronium Major
- Magnesium + Rocuronium Major
- Magnesium + Vecuronium Major
- Amikacin + Magnesium Moderate
- Amphotericin b deoxycholate + Magnesium Moderate
Other interactions of Amiloride
- Amiloride + Eplerenone Contraindicated
- Amiloride + Spironolactone Contraindicated
- Amiloride + Triamterene Contraindicated
- Aceclofenac + Amiloride Major
- Acemetacin + Amiloride Major
- Amiloride + Amlodipine-benazepril Major
Frequently asked questions
Can I take Amiloride with Magnesium?
MediHelp rates the interaction as minor. Amiloride and Magnesium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Amiloride reduces urinary magnesium loss and may raise serum magnesium slightly. This is generally beneficial, but accumulation could occur with magnesium supplements in renal impairment.
How serious is the interaction between Amiloride and Magnesium?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action is usually needed. Monitor magnesium in patients with renal impairment taking magnesium supplements.
What other medicines interact with Magnesium?
MediHelp also lists interactions of Magnesium with, for example, Ciprofloxacin, Pancuronium, Rocuronium. The full list is on the Magnesium page.
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