Drug interactions
Aminohippurate + Celecoxib
Severity: Minor
Aminohippurate and Celecoxib: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Aminohippurate is used as a diagnostic agent to estimate renal plasma flow and is secreted by organic anion transporters. Anionic drugs may compete for this secretion and alter the test result, but celecoxib is highly protein bound and the clinical effect is small.
What this interaction means in plain words
Aminohippurate and Celecoxib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible competition for renal tubular organic anion secretion.
What to do
Be aware that the renal plasma flow estimate could be affected. Interpret results with this in mind if celecoxib cannot be withheld.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Celecoxib
- Celecoxib + Ketorolac Contraindicated
- Celecoxib + Ketorolac intranasal Contraindicated
- Aceclofenac + Celecoxib Major
- Acemetacin + Celecoxib Major
- Amiloride + Celecoxib Major
- Apixaban + Celecoxib Major
Frequently asked questions
Can I take Aminohippurate with Celecoxib?
MediHelp rates the interaction as minor. Aminohippurate and Celecoxib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Aminohippurate is used as a diagnostic agent to estimate renal plasma flow and is secreted by organic anion transporters. Anionic drugs may compete for this secretion and alter the test result, but celecoxib is highly protein bound and the clinical effect is small.
How serious is the interaction between Aminohippurate and Celecoxib?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Be aware that the renal plasma flow estimate could be affected. Interpret results with this in mind if celecoxib cannot be withheld.
What other medicines interact with Celecoxib?
MediHelp also lists interactions of Celecoxib with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Celecoxib page.
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