Drug interactions
Aminohippurate + Ketoprofen
Severity: Minor
Aminohippurate and Ketoprofen: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Aminohippurate is used as a diagnostic agent to measure renal plasma flow, and organic acids like ketoprofen compete for the same tubular secretion pathway. This may raise aminohippurate levels and distort the test result.
What this interaction means in plain words
Aminohippurate and Ketoprofen have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Competition for renal organic anion transporter-mediated tubular secretion.
What to do
Interpret renal plasma flow measurements cautiously in patients taking ketoprofen, and consider withholding the NSAID before testing if feasible.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ketoprofen
- Ketoprofen + Ketorolac Contraindicated
- Ketoprofen + Ketorolac intranasal Contraindicated
- Aceclofenac + Ketoprofen Major
- Acemetacin + Ketoprofen Major
- Acetylsalicylic acid + Ketoprofen Major
- Alteplase + Ketoprofen Major
Frequently asked questions
Can I take Aminohippurate with Ketoprofen?
MediHelp rates the interaction as minor. Aminohippurate and Ketoprofen have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Aminohippurate is used as a diagnostic agent to measure renal plasma flow, and organic acids like ketoprofen compete for the same tubular secretion pathway. This may raise aminohippurate levels and distort the test result.
How serious is the interaction between Aminohippurate and Ketoprofen?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Interpret renal plasma flow measurements cautiously in patients taking ketoprofen, and consider withholding the NSAID before testing if feasible.
What other medicines interact with Ketoprofen?
MediHelp also lists interactions of Ketoprofen with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Ketoprofen page.
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