Drug reference
ketoprofen
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Musculoskeletal (NSAIDs)
Mechanism of action
Inhibits synthesis of prostaglandins in body tissues by inhibiting at least 2 cyclooxygenase isoenzymes, cyclooxygenase-1 (COX-1) and -2 (COX-2) May inhibit chemotaxis, may alter lymphocyte activity, decrease proinflammatory cytokine activity, and may inhibit neutrophil aggregation. These effects may contribute to its anti-inflammatory activity.
Common side effects
- Increased liver function test
- Dyspepsia
- Dizziness
- Headache
- Upper GI ulcers, 3-6 mth treatment
Contraindications
- Hypersensitivity to drug or excipients Patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs For treatment of peri-operative pain in the setting of coronary artery bypass graft (CABG) surgery
Related conditions
Frequently asked questions
What drug class is ketoprofen?
ketoprofen belongs to: Musculoskeletal.
How does ketoprofen work?
Inhibits synthesis of prostaglandins in body tissues by inhibiting at least 2 cyclooxygenase isoenzymes, cyclooxygenase-1 (COX-1) and -2 (COX-2) May inhibit chemotaxis, may alter lymphocyte activity, decrease proinflammatory cytokine activity, and may inhibit neutrophil aggregation. These effects may contribute to its anti-inflammatory activity.
What are the common side effects of ketoprofen?
Increased liver function test, Dyspepsia, Dizziness, Headache, Upper GI ulcers, 3-6 mth treatment
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