Drug interactions
Aminohippurate + Oxaprozin
Severity: Minor
Aminohippurate and Oxaprozin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Aminohippurate is secreted by renal organic anion transporters, and NSAIDs compete for this pathway. This can reduce aminohippurate clearance and bias renal plasma flow measurements.
What this interaction means in plain words
Aminohippurate and Oxaprozin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Competition for renal tubular organic anion transport.
What to do
Interpret PAH clearance results with awareness of NSAID use, and consider holding oxaprozin before renal plasma flow testing.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Oxaprozin
- Ketorolac intranasal + Oxaprozin Contraindicated
- Ketorolac + Oxaprozin Contraindicated
- Aceclofenac + Oxaprozin Major
- Acemetacin + Oxaprozin Major
- Acetylsalicylic acid + Oxaprozin Major
- Alteplase + Oxaprozin Major
Frequently asked questions
Can I take Aminohippurate with Oxaprozin?
MediHelp rates the interaction as minor. Aminohippurate and Oxaprozin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Aminohippurate is secreted by renal organic anion transporters, and NSAIDs compete for this pathway. This can reduce aminohippurate clearance and bias renal plasma flow measurements.
How serious is the interaction between Aminohippurate and Oxaprozin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Interpret PAH clearance results with awareness of NSAID use, and consider holding oxaprozin before renal plasma flow testing.
What other medicines interact with Oxaprozin?
MediHelp also lists interactions of Oxaprozin with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Oxaprozin page.
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