Drug reference
oxaprozin
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Musculoskeletal (NSAIDs)
Mechanism of action
Inhibits synthesis of prostaglandins in body tissues by inhibiting at least 2 cyclooxygenase isoenzymes, cyclooxygenase-1 (COX-1) and -2 (COX-2). May inhibit chemotaxis, may alter lymphocyte activity, decrease proinflammatory cytokine activity, and may inhibit neutrophil aggregation. These effects may contribute to its anti-inflammatory activity.
Common side effects
- Indigestion
- Constipation
- Anemia
- GI ulcer
- Abdominal pain
Contraindications
- Known hypersensitivity (eg, anaphylactic reactions and serious skin reactions) to oxaprozin or any components of the drug product History of asthma, urticaria, or other allergic-type reactions after taking aspirin or other NSAIDs In the setting of CABG surgery
Related conditions
Frequently asked questions
What drug class is oxaprozin?
oxaprozin belongs to: Musculoskeletal.
How does oxaprozin work?
Inhibits synthesis of prostaglandins in body tissues by inhibiting at least 2 cyclooxygenase isoenzymes, cyclooxygenase-1 (COX-1) and -2 (COX-2). May inhibit chemotaxis, may alter lymphocyte activity, decrease proinflammatory cytokine activity, and may inhibit neutrophil aggregation. These effects may contribute to its anti-inflammatory activity.
What are the common side effects of oxaprozin?
Indigestion, Constipation, Anemia, GI ulcer, Abdominal pain
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