Drug interactions
Aminohippurate + Sulindac
Severity: Minor
Aminohippurate and Sulindac: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Aminohippurate is used as a diagnostic agent for measuring renal plasma flow. Sulindac and its metabolites are organic anions that may compete for tubular secretion, potentially affecting the test result.
What this interaction means in plain words
Aminohippurate and Sulindac have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Competition for organic anion transporter-mediated renal tubular secretion.
What to do
Be aware that results of renal plasma flow testing may be affected. Consider withholding the NSAID before testing if feasible.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Sulindac
- Ketorolac intranasal + Sulindac Contraindicated
- Ketorolac + Sulindac Contraindicated
- Aceclofenac + Sulindac Major
- Acetylsalicylic acid + Sulindac Major
- Alteplase + Sulindac Major
- Amiloride + Sulindac Major
Frequently asked questions
Can I take Aminohippurate with Sulindac?
MediHelp rates the interaction as minor. Aminohippurate and Sulindac have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Aminohippurate is used as a diagnostic agent for measuring renal plasma flow. Sulindac and its metabolites are organic anions that may compete for tubular secretion, potentially affecting the test result.
How serious is the interaction between Aminohippurate and Sulindac?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Be aware that results of renal plasma flow testing may be affected. Consider withholding the NSAID before testing if feasible.
What other medicines interact with Sulindac?
MediHelp also lists interactions of Sulindac with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Sulindac page.
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