Drug interactions
Amiodarone + Celiprolol
Severity: Moderate
Amiodarone and Celiprolol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs slow heart rate and AV conduction. Combined use can cause symptomatic bradycardia, AV block or hypotension.
What this interaction means in plain words
Amiodarone and Celiprolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive negative chronotropic and dromotropic effects from beta-blockade plus amiodarone.
What to do
Monitor heart rate, blood pressure and ECG, especially when starting or titrating. Reduce the beta-blocker dose if bradycardia or conduction delay develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Amiodarone
- Amiodarone + Amisulpride Contraindicated
- Amiodarone + Arsenic trioxide Contraindicated
- Amiodarone + Dofetilide Contraindicated
- Amiodarone + Dronedarone Contraindicated
- Amiodarone + Droperidol Contraindicated
- Amiodarone + Eliglustat Contraindicated
Frequently asked questions
Can I take Amiodarone with Celiprolol?
MediHelp rates the interaction as moderate. Amiodarone and Celiprolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs slow heart rate and AV conduction. Combined use can cause symptomatic bradycardia, AV block or hypotension.
How serious is the interaction between Amiodarone and Celiprolol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate, blood pressure and ECG, especially when starting or titrating. Reduce the beta-blocker dose if bradycardia or conduction delay develops.
What other medicines interact with Amiodarone?
MediHelp also lists interactions of Amiodarone with, for example, Amisulpride, Arsenic trioxide, Dofetilide. The full list is on the Amiodarone page.
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