Drug interactions
Amiodarone + Deferasirox
Severity: Minor
Amiodarone and Deferasirox: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Deferasirox is a weak inducer of CYP3A4 and might slightly reduce amiodarone levels. Clinical significance is likely small.
What this interaction means in plain words
Amiodarone and Deferasirox have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amiodarone belongs to Cardiovascular; Deferasirox belongs to Miscellaneous.
Why it happens
Weak CYP3A4 induction by deferasirox may increase amiodarone metabolism.
What to do
Monitor rhythm control and consider checking amiodarone response if arrhythmia recurs after deferasirox is started.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amiodarone
- Amiodarone + Amisulpride Contraindicated
- Amiodarone + Arsenic trioxide Contraindicated
- Amiodarone + Dofetilide Contraindicated
- Amiodarone + Dronedarone Contraindicated
- Amiodarone + Droperidol Contraindicated
- Amiodarone + Eliglustat Contraindicated
Other interactions of Deferasirox
Frequently asked questions
Can I take Amiodarone with Deferasirox?
MediHelp rates the interaction as minor. Amiodarone and Deferasirox have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Deferasirox is a weak inducer of CYP3A4 and might slightly reduce amiodarone levels. Clinical significance is likely small.
How serious is the interaction between Amiodarone and Deferasirox?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor rhythm control and consider checking amiodarone response if arrhythmia recurs after deferasirox is started.
What other medicines interact with Amiodarone?
MediHelp also lists interactions of Amiodarone with, for example, Amisulpride, Arsenic trioxide, Dofetilide. The full list is on the Amiodarone page.
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