Drug interactions
Amiodarone + Neomycin po
Severity: Minor
Amiodarone and Neomycin po: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral neomycin is poorly absorbed, so any increase in its exposure through P-glycoprotein inhibition by amiodarone is unlikely to matter clinically.
What this interaction means in plain words
Amiodarone and Neomycin po have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical P-glycoprotein inhibition by amiodarone; neomycin has minimal oral absorption.
What to do
No action is generally required. Consider monitoring renal function if neomycin is used long term or renal impairment is present.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amiodarone
- Amiodarone + Amisulpride Contraindicated
- Amiodarone + Arsenic trioxide Contraindicated
- Amiodarone + Dofetilide Contraindicated
- Amiodarone + Dronedarone Contraindicated
- Amiodarone + Droperidol Contraindicated
- Amiodarone + Eliglustat Contraindicated
Frequently asked questions
Can I take Amiodarone with Neomycin po?
MediHelp rates the interaction as minor. Amiodarone and Neomycin po have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oral neomycin is poorly absorbed, so any increase in its exposure through P-glycoprotein inhibition by amiodarone is unlikely to matter clinically.
How serious is the interaction between Amiodarone and Neomycin po?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action is generally required. Consider monitoring renal function if neomycin is used long term or renal impairment is present.
What other medicines interact with Amiodarone?
MediHelp also lists interactions of Amiodarone with, for example, Amisulpride, Arsenic trioxide, Dofetilide. The full list is on the Amiodarone page.
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