Drug interactions
Amiodarone + Telmisartan-amlodipine
Severity: Minor
Amiodarone and Telmisartan-amlodipine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
The legacy hint refers to a hydrochlorothiazide component that is not present in telmisartan-amlodipine, and no clinically established interaction with this combination is described. Amlodipine may add to amiodarone-related bradycardia and hypotension, but the interaction is not well characterized.
What this interaction means in plain words
Amiodarone and Telmisartan-amlodipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amiodarone belongs to Cardiovascular; Telmisartan-amlodipine belongs to Cardiovascular.
Why it happens
Possible additive hypotensive and negative chronotropic effects; no established pharmacokinetic mechanism.
What to do
Monitor heart rate and blood pressure when starting or adjusting amiodarone.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Telmisartan-amlodipine
- Aliskiren + Telmisartan-amlodipine Contraindicated
- Sparsentan + Telmisartan-amlodipine Contraindicated
- Amifostine + Telmisartan-amlodipine Major
- Amiloride + Telmisartan-amlodipine Major
- Benazepril + Telmisartan-amlodipine Major
- Candesartan + Telmisartan-amlodipine Major
Other interactions of Amiodarone
- Amiodarone + Amisulpride Contraindicated
- Amiodarone + Arsenic trioxide Contraindicated
- Amiodarone + Dofetilide Contraindicated
- Amiodarone + Dronedarone Contraindicated
- Amiodarone + Droperidol Contraindicated
- Amiodarone + Eliglustat Contraindicated
Frequently asked questions
Can I take Amiodarone with Telmisartan-amlodipine?
MediHelp rates the interaction as minor. Amiodarone and Telmisartan-amlodipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. The legacy hint refers to a hydrochlorothiazide component that is not present in telmisartan-amlodipine, and no clinically established interaction with this combination is described. Amlodipine may add to amiodarone-related bradycardia and hypotension, but the interaction is not well characterized.
How serious is the interaction between Amiodarone and Telmisartan-amlodipine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and blood pressure when starting or adjusting amiodarone.
What other medicines interact with Telmisartan-amlodipine?
MediHelp also lists interactions of Telmisartan-amlodipine with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Telmisartan-amlodipine page.
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