Drug interactions
Amlodipine + Calcium citrate
Severity: Minor
Amlodipine and Calcium citrate: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral calcium citrate has very little effect on amlodipine in practice. A large increase in serum calcium could theoretically reduce the antihypertensive effect of the calcium channel blocker. Clinically relevant loss of blood pressure control is uncommon at usual supplement doses.
What this interaction means in plain words
Amlodipine and Calcium citrate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Raised serum calcium can theoretically antagonize calcium channel blockade pharmacodynamically.
What to do
No routine change is needed; check blood pressure if high-dose calcium or vitamin D is started. Check serum calcium if blood pressure control worsens unexpectedly.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine
- Amifostine + Amlodipine Major
- Amlodipine + Ombitasvir / paritaprevir / ritonavir and dasabuvir Major
- Activated Charcoal + Amlodipine Moderate
- Aldesleukin + Amlodipine Moderate
- Alfuzosin + Amlodipine Moderate
- Amlodipine + Apalutamide Moderate
Frequently asked questions
Can I take Amlodipine with Calcium citrate?
MediHelp rates the interaction as minor. Amlodipine and Calcium citrate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oral calcium citrate has very little effect on amlodipine in practice. A large increase in serum calcium could theoretically reduce the antihypertensive effect of the calcium channel blocker. Clinically relevant loss of blood pressure control is uncommon at usual supplement doses.
How serious is the interaction between Amlodipine and Calcium citrate?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed; check blood pressure if high-dose calcium or vitamin D is started. Check serum calcium if blood pressure control worsens unexpectedly.
What other medicines interact with Amlodipine?
MediHelp also lists interactions of Amlodipine with, for example, Amifostine, Ombitasvir / paritaprevir / ritonavir and dasabuvir, Activated Charcoal. The full list is on the Amlodipine page.
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