Drug interactions
Amlodipine + Celiprolol
Severity: Moderate
Amlodipine and Celiprolol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs lower blood pressure, so combining them gives additive antihypertensive effect. This is often used intentionally but can cause hypotension, dizziness or reflex changes in heart rate. Celiprolol has vasodilating properties that may add to this.
What this interaction means in plain words
Amlodipine and Celiprolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive pharmacodynamic blood pressure lowering from beta-blockade with vasodilation and dihydropyridine calcium channel blockade.
What to do
Monitor blood pressure and heart rate when combining or changing doses, and adjust either drug if hypotension or symptomatic bradycardia develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Amlodipine
- Amifostine + Amlodipine Major
- Amlodipine + Ombitasvir / paritaprevir / ritonavir and dasabuvir Major
- Activated Charcoal + Amlodipine Moderate
- Aldesleukin + Amlodipine Moderate
- Alfuzosin + Amlodipine Moderate
- Amlodipine + Apalutamide Moderate
Frequently asked questions
Can I take Amlodipine with Celiprolol?
MediHelp rates the interaction as moderate. Amlodipine and Celiprolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs lower blood pressure, so combining them gives additive antihypertensive effect. This is often used intentionally but can cause hypotension, dizziness or reflex changes in heart rate. Celiprolol has vasodilating properties that may add to this.
How serious is the interaction between Amlodipine and Celiprolol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate when combining or changing doses, and adjust either drug if hypotension or symptomatic bradycardia develops.
What other medicines interact with Amlodipine?
MediHelp also lists interactions of Amlodipine with, for example, Amifostine, Ombitasvir / paritaprevir / ritonavir and dasabuvir, Activated Charcoal. The full list is on the Amlodipine page.
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