Drug interactions
Amlodipine + Deferasirox
Severity: Minor
Amlodipine and Deferasirox: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Deferasirox may induce CYP3A4 and lower amlodipine concentrations. The effect is probably modest, but blood pressure control could be reduced.
What this interaction means in plain words
Amlodipine and Deferasirox have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amlodipine belongs to Cardiovascular; Deferasirox belongs to Miscellaneous.
Why it happens
Possible CYP3A4 induction by deferasirox increasing amlodipine metabolism.
What to do
Monitor blood pressure when deferasirox is started or stopped. Increase the amlodipine dose only if control is lost.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine
- Amifostine + Amlodipine Major
- Amlodipine + Ombitasvir / paritaprevir / ritonavir and dasabuvir Major
- Activated Charcoal + Amlodipine Moderate
- Aldesleukin + Amlodipine Moderate
- Alfuzosin + Amlodipine Moderate
- Amlodipine + Apalutamide Moderate
Other interactions of Deferasirox
Frequently asked questions
Can I take Amlodipine with Deferasirox?
MediHelp rates the interaction as minor. Amlodipine and Deferasirox have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Deferasirox may induce CYP3A4 and lower amlodipine concentrations. The effect is probably modest, but blood pressure control could be reduced.
How serious is the interaction between Amlodipine and Deferasirox?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure when deferasirox is started or stopped. Increase the amlodipine dose only if control is lost.
What other medicines interact with Amlodipine?
MediHelp also lists interactions of Amlodipine with, for example, Amifostine, Ombitasvir / paritaprevir / ritonavir and dasabuvir, Activated Charcoal. The full list is on the Amlodipine page.
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