Drug interactions
Amlodipine + Trimagnesium
Severity: Minor
Amlodipine and Trimagnesium: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Magnesium has calcium-antagonist properties, and with a calcium channel blocker it may add to blood pressure lowering or neuromuscular weakness. This is mainly relevant with parenteral or high-dose magnesium.
What this interaction means in plain words
Amlodipine and Trimagnesium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive pharmacodynamic calcium-antagonist effects on vascular and muscle tissue.
What to do
With intravenous or high-dose magnesium, monitor blood pressure and neuromuscular function. Oral supplement doses rarely need changes.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine
- Amifostine + Amlodipine Major
- Amlodipine + Ombitasvir / paritaprevir / ritonavir and dasabuvir Major
- Activated Charcoal + Amlodipine Moderate
- Aldesleukin + Amlodipine Moderate
- Alfuzosin + Amlodipine Moderate
- Amlodipine + Apalutamide Moderate
Frequently asked questions
Can I take Amlodipine with Trimagnesium?
MediHelp rates the interaction as minor. Amlodipine and Trimagnesium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Magnesium has calcium-antagonist properties, and with a calcium channel blocker it may add to blood pressure lowering or neuromuscular weakness. This is mainly relevant with parenteral or high-dose magnesium.
How serious is the interaction between Amlodipine and Trimagnesium?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: With intravenous or high-dose magnesium, monitor blood pressure and neuromuscular function. Oral supplement doses rarely need changes.
What other medicines interact with Amlodipine?
MediHelp also lists interactions of Amlodipine with, for example, Amifostine, Ombitasvir / paritaprevir / ritonavir and dasabuvir, Activated Charcoal. The full list is on the Amlodipine page.
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