Drug interactions
Amlodipine-benazepril + Etrasimod
Severity: Minor
Amlodipine-benazepril and Etrasimod: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Etrasimod can transiently slow heart rate and delay AV conduction when started. Amlodipine is a dihydropyridine without significant effect on conduction, so the interaction is mostly theoretical and limited to additive hemodynamic effects.
What this interaction means in plain words
Amlodipine-benazepril and Etrasimod have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amlodipine-benazepril belongs to Cardiovascular; Etrasimod belongs to Gastrointestinal Tract.
Why it happens
Possible additive hemodynamic effects; etrasimod S1P receptor modulation slows heart rate while amlodipine acts mainly on vascular tone.
What to do
Monitor heart rate and blood pressure when initiating etrasimod. No routine dose change is needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-benazepril
- Aliskiren + Amlodipine-benazepril Contraindicated
- Amlodipine-benazepril + Sacubitril / valsartan Contraindicated
- Aldesleukin + Amlodipine-benazepril Major
- Amifostine + Amlodipine-benazepril Major
- Amiloride + Amlodipine-benazepril Major
- Amlodipine-benazepril + Azilsartan Major
Other interactions of Etrasimod
- Abatacept + Etrasimod Major
- Amiodarone + Etrasimod Major
- Anagrelide + Etrasimod Major
- Anakinra + Etrasimod Major
- Anti-thymocyte + Etrasimod Major
- Asenapine + Etrasimod Major
Frequently asked questions
Can I take Amlodipine-benazepril with Etrasimod?
MediHelp rates the interaction as minor. Amlodipine-benazepril and Etrasimod have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Etrasimod can transiently slow heart rate and delay AV conduction when started. Amlodipine is a dihydropyridine without significant effect on conduction, so the interaction is mostly theoretical and limited to additive hemodynamic effects.
How serious is the interaction between Amlodipine-benazepril and Etrasimod?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and blood pressure when initiating etrasimod. No routine dose change is needed.
What other medicines interact with Amlodipine-benazepril?
MediHelp also lists interactions of Amlodipine-benazepril with, for example, Aliskiren, Sacubitril / valsartan, Aldesleukin. The full list is on the Amlodipine-benazepril page.
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