Drug interactions
Amlodipine-benazepril + Oxcarbazepine
Severity: Minor
Amlodipine-benazepril and Oxcarbazepine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oxcarbazepine is a weak inducer of CYP3A4 and may lower amlodipine exposure. This could modestly reduce blood pressure control, although the effect is generally small.
What this interaction means in plain words
Amlodipine-benazepril and Oxcarbazepine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amlodipine-benazepril belongs to Cardiovascular; Oxcarbazepine belongs to Central Nervous System.
Why it happens
Weak induction of CYP3A4 by oxcarbazepine increases amlodipine metabolism.
What to do
Monitor blood pressure after oxcarbazepine is started or stopped. Increase the amlodipine dose if control is lost.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-benazepril
- Aliskiren + Amlodipine-benazepril Contraindicated
- Amlodipine-benazepril + Sacubitril / valsartan Contraindicated
- Aldesleukin + Amlodipine-benazepril Major
- Amifostine + Amlodipine-benazepril Major
- Amiloride + Amlodipine-benazepril Major
- Amlodipine-benazepril + Azilsartan Major
Other interactions of Oxcarbazepine
- Cabotegravir + Oxcarbazepine Contraindicated
- Oxcarbazepine + Rilpivirine Contraindicated
- Artemether / lumefantrine + Oxcarbazepine Major
- Atazanavir + Oxcarbazepine Major
- Benzhydrocodone / acetaminophen + Oxcarbazepine Major
- Bictegravir + Oxcarbazepine Major
Frequently asked questions
Can I take Amlodipine-benazepril with Oxcarbazepine?
MediHelp rates the interaction as minor. Amlodipine-benazepril and Oxcarbazepine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oxcarbazepine is a weak inducer of CYP3A4 and may lower amlodipine exposure. This could modestly reduce blood pressure control, although the effect is generally small.
How serious is the interaction between Amlodipine-benazepril and Oxcarbazepine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure after oxcarbazepine is started or stopped. Increase the amlodipine dose if control is lost.
What other medicines interact with Amlodipine-benazepril?
MediHelp also lists interactions of Amlodipine-benazepril with, for example, Aliskiren, Sacubitril / valsartan, Aldesleukin. The full list is on the Amlodipine-benazepril page.
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