Drug interactions
Amlodipine-benazepril + Patiromer
Severity: Minor
Amlodipine-benazepril and Patiromer: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Patiromer is a cation-exchange polymer that can bind some oral drugs in the gut. Studies with amlodipine found no clinically relevant effect on its absorption, and no interaction with benazepril is expected. Patiromer may in fact help offset ACE inhibitor-related hyperkalemia.
What this interaction means in plain words
Amlodipine-benazepril and Patiromer have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amlodipine-benazepril belongs to Cardiovascular; Patiromer belongs to Miscellaneous.
Why it happens
Potential binding in the gastrointestinal tract, but no clinically important effect on absorption was observed.
What to do
Separate other oral medications from patiromer by 3 hours as the labeling advises, although none is specifically required for amlodipine. Monitor serum potassium.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-benazepril
- Aliskiren + Amlodipine-benazepril Contraindicated
- Amlodipine-benazepril + Sacubitril / valsartan Contraindicated
- Aldesleukin + Amlodipine-benazepril Major
- Amifostine + Amlodipine-benazepril Major
- Amiloride + Amlodipine-benazepril Major
- Amlodipine-benazepril + Azilsartan Major
Other interactions of Patiromer
- Alogliptin-metformin + Patiromer Moderate
- Canagliflozin-metformin + Patiromer Moderate
- Carvedilol + Patiromer Moderate
- Ciprofloxacin + Patiromer Moderate
- Dapagliflozin-metformin + Patiromer Moderate
- Empagliflozin-metformin + Patiromer Moderate
Frequently asked questions
Can I take Amlodipine-benazepril with Patiromer?
MediHelp rates the interaction as minor. Amlodipine-benazepril and Patiromer have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Patiromer is a cation-exchange polymer that can bind some oral drugs in the gut. Studies with amlodipine found no clinically relevant effect on its absorption, and no interaction with benazepril is expected. Patiromer may in fact help offset ACE inhibitor-related hyperkalemia.
How serious is the interaction between Amlodipine-benazepril and Patiromer?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate other oral medications from patiromer by 3 hours as the labeling advises, although none is specifically required for amlodipine. Monitor serum potassium.
What other medicines interact with Amlodipine-benazepril?
MediHelp also lists interactions of Amlodipine-benazepril with, for example, Aliskiren, Sacubitril / valsartan, Aldesleukin. The full list is on the Amlodipine-benazepril page.
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