Drug interactions
Amlodipine-benazepril + Rocuronium
Severity: Minor
Amlodipine-benazepril and Rocuronium: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Calcium channel blockers may potentiate neuromuscular blockade from rocuronium. Recovery from blockade may be prolonged, although the effect is usually small.
What this interaction means in plain words
Amlodipine-benazepril and Rocuronium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amlodipine-benazepril belongs to Cardiovascular; Rocuronium belongs to Musculoskeletal.
Why it happens
Calcium channel blockade reduces presynaptic acetylcholine release, adding to nondepolarizing blockade.
What to do
Use neuromuscular monitoring and titrate rocuronium to effect. Expect possibly slower recovery.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-benazepril
- Aliskiren + Amlodipine-benazepril Contraindicated
- Amlodipine-benazepril + Sacubitril / valsartan Contraindicated
- Aldesleukin + Amlodipine-benazepril Major
- Amifostine + Amlodipine-benazepril Major
- Amiloride + Amlodipine-benazepril Major
- Amlodipine-benazepril + Azilsartan Major
Other interactions of Rocuronium
Frequently asked questions
Can I take Amlodipine-benazepril with Rocuronium?
MediHelp rates the interaction as minor. Amlodipine-benazepril and Rocuronium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Calcium channel blockers may potentiate neuromuscular blockade from rocuronium. Recovery from blockade may be prolonged, although the effect is usually small.
How serious is the interaction between Amlodipine-benazepril and Rocuronium?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use neuromuscular monitoring and titrate rocuronium to effect. Expect possibly slower recovery.
What other medicines interact with Amlodipine-benazepril?
MediHelp also lists interactions of Amlodipine-benazepril with, for example, Aliskiren, Sacubitril / valsartan, Aldesleukin. The full list is on the Amlodipine-benazepril page.
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