Drug interactions
Amlodipine-benazepril + Terazosin
Severity: Moderate
Amlodipine-benazepril and Terazosin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Terazosin is an alpha-1 blocker that can cause first-dose and orthostatic hypotension, and the combination with an ACE inhibitor and a calcium channel blocker intensifies this. Dizziness and fainting are the main concerns.
What this interaction means in plain words
Amlodipine-benazepril and Terazosin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amlodipine-benazepril belongs to Cardiovascular; Terazosin belongs to Genitourinary.
Why it happens
Additive blood pressure lowering from alpha-1 blockade, ACE inhibition and calcium channel blockade.
What to do
Give the first terazosin dose at bedtime and monitor blood pressure and orthostatic symptoms. Adjust doses of the antihypertensives if hypotension persists.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Amlodipine-benazepril
- Aliskiren + Amlodipine-benazepril Contraindicated
- Amlodipine-benazepril + Sacubitril / valsartan Contraindicated
- Aldesleukin + Amlodipine-benazepril Major
- Amifostine + Amlodipine-benazepril Major
- Amiloride + Amlodipine-benazepril Major
- Amlodipine-benazepril + Azilsartan Major
Other interactions of Terazosin
- Alfuzosin + Terazosin Major
- Amifostine + Terazosin Major
- Avanafil + Terazosin Major
- Doxazosin + Terazosin Major
- Dutasteride-tamsulosin + Terazosin Major
- Lofexidine + Terazosin Major
Frequently asked questions
Can I take Amlodipine-benazepril with Terazosin?
MediHelp rates the interaction as moderate. Amlodipine-benazepril and Terazosin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Terazosin is an alpha-1 blocker that can cause first-dose and orthostatic hypotension, and the combination with an ACE inhibitor and a calcium channel blocker intensifies this. Dizziness and fainting are the main concerns.
How serious is the interaction between Amlodipine-benazepril and Terazosin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give the first terazosin dose at bedtime and monitor blood pressure and orthostatic symptoms. Adjust doses of the antihypertensives if hypotension persists.
What other medicines interact with Amlodipine-benazepril?
MediHelp also lists interactions of Amlodipine-benazepril with, for example, Aliskiren, Sacubitril / valsartan, Aldesleukin. The full list is on the Amlodipine-benazepril page.
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