Drug interactions
Amlodipine-hydrochlorothiazide-valsartan + Forskolin
Severity: Minor
Amlodipine-hydrochlorothiazide-valsartan and Forskolin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Forskolin activates adenylyl cyclase and causes vasodilation, so it could add to the blood pressure lowering of amlodipine and hydrochlorothiazide. Clinical data are limited.
What this interaction means in plain words
Amlodipine-hydrochlorothiazide-valsartan and Forskolin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical additive vasodilatory effect through increased cyclic AMP.
What to do
Monitor blood pressure in patients who use forskolin supplements and counsel them to report dizziness.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-hydrochlorothiazide-valsartan
- Aliskiren + Amlodipine-hydrochlorothiazide-valsartan Contraindicated
- Amlodipine-hydrochlorothiazide-valsartan + Dofetilide Contraindicated
- Amlodipine-hydrochlorothiazide-valsartan + Sparsentan Contraindicated
- Aceclofenac + Amlodipine-hydrochlorothiazide-valsartan Major
- Aldesleukin + Amlodipine-hydrochlorothiazide-valsartan Major
- Amifostine + Amlodipine-hydrochlorothiazide-valsartan Major
Frequently asked questions
Can I take Amlodipine-hydrochlorothiazide-valsartan with Forskolin?
MediHelp rates the interaction as minor. Amlodipine-hydrochlorothiazide-valsartan and Forskolin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Forskolin activates adenylyl cyclase and causes vasodilation, so it could add to the blood pressure lowering of amlodipine and hydrochlorothiazide. Clinical data are limited.
How serious is the interaction between Amlodipine-hydrochlorothiazide-valsartan and Forskolin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure in patients who use forskolin supplements and counsel them to report dizziness.
What other medicines interact with Amlodipine-hydrochlorothiazide-valsartan?
MediHelp also lists interactions of Amlodipine-hydrochlorothiazide-valsartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Amlodipine-hydrochlorothiazide-valsartan page.
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