Drug interactions
Amlodipine-olmesartan + Calcium acetate
Severity: Minor
Amlodipine-olmesartan and Calcium acetate: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Calcium salts can theoretically blunt the effect of calcium channel blockers, and high serum calcium has been reported to reduce their benefit. With oral calcium acetate used as a phosphate binder, the effect is generally small. It matters mainly if hypercalcemia develops.
What this interaction means in plain words
Amlodipine-olmesartan and Calcium acetate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amlodipine-olmesartan belongs to Cardiovascular; Calcium acetate belongs to Genitourinary.
Why it happens
Raised extracellular calcium may functionally oppose L-type calcium channel blockade by amlodipine.
What to do
Monitor serum calcium and blood pressure in patients on calcium acetate, and treat hypercalcemia if present.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-olmesartan
- Aliskiren + Amlodipine-olmesartan Contraindicated
- Amlodipine-olmesartan + Sparsentan Contraindicated
- Amifostine + Amlodipine-olmesartan Major
- Amiloride + Amlodipine-olmesartan Major
- Amlodipine-olmesartan + Benazepril Major
- Amlodipine-olmesartan + Captopril Major
Other interactions of Calcium acetate
Frequently asked questions
Can I take Amlodipine-olmesartan with Calcium acetate?
MediHelp rates the interaction as minor. Amlodipine-olmesartan and Calcium acetate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Calcium salts can theoretically blunt the effect of calcium channel blockers, and high serum calcium has been reported to reduce their benefit. With oral calcium acetate used as a phosphate binder, the effect is generally small. It matters mainly if hypercalcemia develops.
How serious is the interaction between Amlodipine-olmesartan and Calcium acetate?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum calcium and blood pressure in patients on calcium acetate, and treat hypercalcemia if present.
What other medicines interact with Amlodipine-olmesartan?
MediHelp also lists interactions of Amlodipine-olmesartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Amlodipine-olmesartan page.
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