Drug interactions
Amphotericin b deoxycholate + Formoterol-mometasone
Severity: Moderate
Amphotericin b deoxycholate and Formoterol-mometasone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Amphotericin B commonly causes potassium wasting, and corticosteroids and formoterol can lower potassium as well. Together hypokalemia may be intensified, raising the risk of arrhythmia, although inhaled mometasone has low systemic exposure.
What this interaction means in plain words
Amphotericin b deoxycholate and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive hypokalemia through renal potassium loss (amphotericin, corticosteroid) and cellular potassium shift (formoterol).
What to do
Monitor serum potassium and magnesium regularly and replace as needed. Take extra care in patients with cardiac disease or on QT-prolonging drugs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol-mometasone
Frequently asked questions
Can I take Amphotericin b deoxycholate with Formoterol-mometasone?
MediHelp rates the interaction as moderate. Amphotericin b deoxycholate and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Amphotericin B commonly causes potassium wasting, and corticosteroids and formoterol can lower potassium as well. Together hypokalemia may be intensified, raising the risk of arrhythmia, although inhaled mometasone has low systemic exposure.
How serious is the interaction between Amphotericin b deoxycholate and Formoterol-mometasone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and magnesium regularly and replace as needed. Take extra care in patients with cardiac disease or on QT-prolonging drugs.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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