Drug interactions
Artemether / lumefantrine + Formoterol-mometasone
Severity: Major
Artemether / lumefantrine and Formoterol-mometasone: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Artemether/lumefantrine can prolong the QT interval, and formoterol may add to this effect and lower potassium. The combination may increase the risk of torsades de pointes.
What this interaction means in plain words
Artemether / lumefantrine and Formoterol-mometasone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Why it happens
Additive QT prolongation, with beta-2 agonist induced hypokalemia as a further contributor.
What to do
Check a baseline ECG and correct potassium and magnesium before use. Monitor ECG during therapy, or use another bronchodilator during antimalarial treatment if possible.
What to ask your pharmacist
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Other interactions of Formoterol-mometasone
Frequently asked questions
Can I take Artemether / lumefantrine with Formoterol-mometasone?
MediHelp rates the interaction as major. Artemether / lumefantrine and Formoterol-mometasone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Artemether/lumefantrine can prolong the QT interval, and formoterol may add to this effect and lower potassium. The combination may increase the risk of torsades de pointes.
How serious is the interaction between Artemether / lumefantrine and Formoterol-mometasone?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check a baseline ECG and correct potassium and magnesium before use. Monitor ECG during therapy, or use another bronchodilator during antimalarial treatment if possible.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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