Drug interactions
Ampicillin + Bazedoxifene / conjugated estrogens
Severity: Minor
Ampicillin and Bazedoxifene / conjugated estrogens: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Antibiotics have been theorized to reduce enterohepatic recirculation of estrogens by altering gut flora. Pharmacokinetic studies and clinical data have generally not shown a consistent loss of efficacy with ampicillin, and the effect on this menopausal product is unlikely to be meaningful.
What this interaction means in plain words
Ampicillin and Bazedoxifene / conjugated estrogens have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical reduction of gut bacterial deconjugation and enterohepatic recirculation of estrogens.
What to do
No routine action is needed; patients can continue therapy and report breakthrough bleeding or recurrence of vasomotor symptoms.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ampicillin
- Allopurinol + Ampicillin Moderate
- Ampicillin + Bcg vaccine live Moderate
- Ampicillin + Chloramphenicol Moderate
- Ampicillin + Chloroquine Moderate
- Ampicillin + Cholera vaccine Moderate
- Ampicillin + Demeclocycline Moderate
Frequently asked questions
Can I take Ampicillin with Bazedoxifene / conjugated estrogens?
MediHelp rates the interaction as minor. Ampicillin and Bazedoxifene / conjugated estrogens have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Antibiotics have been theorized to reduce enterohepatic recirculation of estrogens by altering gut flora. Pharmacokinetic studies and clinical data have generally not shown a consistent loss of efficacy with ampicillin, and the effect on this menopausal product is unlikely to be meaningful.
How serious is the interaction between Ampicillin and Bazedoxifene / conjugated estrogens?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed; patients can continue therapy and report breakthrough bleeding or recurrence of vasomotor symptoms.
What other medicines interact with Ampicillin?
MediHelp also lists interactions of Ampicillin with, for example, Allopurinol, Bcg vaccine live, Chloramphenicol. The full list is on the Ampicillin page.
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