Drug interactions
Anagrelide + Antithrombin alfa
Severity: Moderate
Anagrelide and Antithrombin alfa: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Antithrombin potentiates heparin-type anticoagulation, while anagrelide inhibits platelet aggregation. Together bleeding risk may increase.
What this interaction means in plain words
Anagrelide and Antithrombin alfa can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive antihemostatic effects: anticoagulation plus platelet inhibition.
What to do
Monitor for bleeding and platelet counts and coagulation parameters during co-use.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Anagrelide
- Anagrelide + Panobinostat Contraindicated
- Anagrelide + Pimozide Contraindicated
- Anagrelide + Thioridazine Contraindicated
- Anagrelide + Vandetanib Contraindicated
- Abrocitinib + Anagrelide Major
- Alfuzosin + Anagrelide Major
Frequently asked questions
Can I take Anagrelide with Antithrombin alfa?
MediHelp rates the interaction as moderate. Anagrelide and Antithrombin alfa can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Antithrombin potentiates heparin-type anticoagulation, while anagrelide inhibits platelet aggregation. Together bleeding risk may increase.
How serious is the interaction between Anagrelide and Antithrombin alfa?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for bleeding and platelet counts and coagulation parameters during co-use.
What other medicines interact with Anagrelide?
MediHelp also lists interactions of Anagrelide with, for example, Panobinostat, Pimozide, Thioridazine. The full list is on the Anagrelide page.
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