Drug reference
anagrelide
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Cardiovascular (Miscellaneous(CVS))
Mechanism of action
Phosphodiesterase 3 (PDE3) inhibitor; inhibits nucleotide PDE and the release of arachidonic acid from phospholipase A2; reduces also platelet production by disrupting the maturation phase of megakaryocytes
Common side effects
- Asthenia
- Palpitations
- Edema
- Headache
- Diarrhea
Known interactions (11)
- anagrelide + pimozide Contraindicated
- anagrelide + thioridazine Contraindicated
- anagrelide + dronedarone Major
- anagrelide + argatroban Moderate
- anagrelide + dalteparin Moderate
- anagrelide + enoxaparin Moderate
- anagrelide + fondaparinux Moderate
- anagrelide + goserelin Moderate
- anagrelide + heparin Moderate
- anagrelide + leuprolide Moderate
- anagrelide + triptorelin Moderate
Related conditions
Frequently asked questions
What drug class is anagrelide?
anagrelide belongs to: Cardiovascular.
How does anagrelide work?
Phosphodiesterase 3 (PDE3) inhibitor; inhibits nucleotide PDE and the release of arachidonic acid from phospholipase A2; reduces also platelet production by disrupting the maturation phase of megakaryocytes
What are the common side effects of anagrelide?
Asthenia, Palpitations, Edema, Headache, Diarrhea
Which drugs interact with anagrelide?
pimozide, thioridazine, dronedarone, argatroban, dalteparin, enoxaparin, fondaparinux, goserelin, heparin, leuprolide, triptorelin
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.