Drug interactions
Anagrelide + Arformoterol
Severity: Moderate
Anagrelide and Arformoterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Anagrelide and the long-acting beta-agonist arformoterol can each prolong QTc and provoke tachyarrhythmias. Combined use may increase the risk of serious ventricular arrhythmias, especially with low potassium or heart disease.
What this interaction means in plain words
Anagrelide and Arformoterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Anagrelide belongs to Cardiovascular; Arformoterol belongs to Respiratory.
Why it happens
Additive QT prolongation with beta-agonist-induced hypokalemia and increased heart rate.
What to do
Obtain a baseline ECG and monitor potassium and magnesium. Watch for palpitations or syncope, and consider alternatives in patients with existing arrhythmia.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Anagrelide
- Anagrelide + Panobinostat Contraindicated
- Anagrelide + Pimozide Contraindicated
- Anagrelide + Thioridazine Contraindicated
- Anagrelide + Vandetanib Contraindicated
- Abrocitinib + Anagrelide Major
- Alfuzosin + Anagrelide Major
Other interactions of Arformoterol
Frequently asked questions
Can I take Anagrelide with Arformoterol?
MediHelp rates the interaction as moderate. Anagrelide and Arformoterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Anagrelide and the long-acting beta-agonist arformoterol can each prolong QTc and provoke tachyarrhythmias. Combined use may increase the risk of serious ventricular arrhythmias, especially with low potassium or heart disease.
How serious is the interaction between Anagrelide and Arformoterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG and monitor potassium and magnesium. Watch for palpitations or syncope, and consider alternatives in patients with existing arrhythmia.
What other medicines interact with Anagrelide?
MediHelp also lists interactions of Anagrelide with, for example, Panobinostat, Pimozide, Thioridazine. The full list is on the Anagrelide page.
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