Drug interactions
Anagrelide + Dabigatran
Severity: Moderate
Anagrelide and Dabigatran: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dabigatran is a direct thrombin inhibitor and anagrelide impairs platelet function. Together bleeding risk is increased, including gastrointestinal and intracranial bleeding.
What this interaction means in plain words
Anagrelide and Dabigatran can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive anticoagulant and antiplatelet effects.
What to do
Monitor for bleeding and follow hemoglobin, platelet count and renal function. Review the need for both drugs regularly.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Anagrelide
- Anagrelide + Panobinostat Contraindicated
- Anagrelide + Pimozide Contraindicated
- Anagrelide + Thioridazine Contraindicated
- Anagrelide + Vandetanib Contraindicated
- Abrocitinib + Anagrelide Major
- Alfuzosin + Anagrelide Major
Frequently asked questions
Can I take Anagrelide with Dabigatran?
MediHelp rates the interaction as moderate. Anagrelide and Dabigatran can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dabigatran is a direct thrombin inhibitor and anagrelide impairs platelet function. Together bleeding risk is increased, including gastrointestinal and intracranial bleeding.
How serious is the interaction between Anagrelide and Dabigatran?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for bleeding and follow hemoglobin, platelet count and renal function. Review the need for both drugs regularly.
What other medicines interact with Anagrelide?
MediHelp also lists interactions of Anagrelide with, for example, Panobinostat, Pimozide, Thioridazine. The full list is on the Anagrelide page.
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