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Drug interactions

Anagrelide + Ginkgo biloba

Severity: Moderate

Anagrelide and Ginkgo biloba: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Ginkgo has been associated with platelet-activating-factor antagonism and isolated bleeding reports, and anagrelide reduces platelet aggregation. Combined use may modestly raise bleeding risk, but clinical evidence is conflicting.

What this interaction means in plain words

Anagrelide and Ginkgo biloba can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Low

Why it happens

Additive antiplatelet effects through different pathways.

What to do

Advise avoiding ginkgo while on anagrelide where feasible. If both are continued, monitor for bruising, bleeding and platelet counts.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Anagrelide with Ginkgo biloba?

MediHelp rates the interaction as moderate. Anagrelide and Ginkgo biloba can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ginkgo has been associated with platelet-activating-factor antagonism and isolated bleeding reports, and anagrelide reduces platelet aggregation. Combined use may modestly raise bleeding risk, but clinical evidence is conflicting.

How serious is the interaction between Anagrelide and Ginkgo biloba?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise avoiding ginkgo while on anagrelide where feasible. If both are continued, monitor for bruising, bleeding and platelet counts.

What other medicines interact with Anagrelide?

MediHelp also lists interactions of Anagrelide with, for example, Panobinostat, Pimozide, Thioridazine. The full list is on the Anagrelide page.

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