Drug interactions
Anakinra + Ublituximab
Severity: Moderate
Anakinra and Ublituximab: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Combining B-cell depletion with IL-1 blockade may increase the risk of serious infection through additive immunosuppression.
What this interaction means in plain words
Anakinra and Ublituximab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Anakinra belongs to Musculoskeletal; Ublituximab belongs to Miscellaneous.
Why it happens
Additive immunosuppression from B-cell depletion and IL-1 receptor antagonism.
What to do
Avoid combining unless clearly needed, and monitor for infection. Screen for hepatitis B before ublituximab.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Anakinra
- Anakinra + Bcg vaccine live Contraindicated
- Anakinra + Measles mumps and rubella vaccine Contraindicated
- Anakinra + Measles mumps and rubella vaccine live Contraindicated
- Anakinra + Measles mumps rubella and varicella vaccine live Contraindicated
- Anakinra + Measles vaccine Contraindicated
- Abatacept + Anakinra Major
Other interactions of Ublituximab
Frequently asked questions
Can I take Anakinra with Ublituximab?
MediHelp rates the interaction as moderate. Anakinra and Ublituximab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Combining B-cell depletion with IL-1 blockade may increase the risk of serious infection through additive immunosuppression.
How serious is the interaction between Anakinra and Ublituximab?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining unless clearly needed, and monitor for infection. Screen for hepatitis B before ublituximab.
What other medicines interact with Anakinra?
MediHelp also lists interactions of Anakinra with, for example, Bcg vaccine live, Measles mumps and rubella vaccine, Measles mumps and rubella vaccine live. The full list is on the Anakinra page.
Full monographs, dosing and an interaction checker in the MediHelp app
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