Drug interactions
Anamu + Argatroban
Severity: Moderate
Anamu and Argatroban: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Anamu (Petiveria alliacea) has been reported to have antiplatelet or anticoagulant-like activity in laboratory studies. Combined use with argatroban could theoretically raise bleeding risk, but clinical data are scarce.
What this interaction means in plain words
Anamu and Argatroban can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Possible additive antiplatelet or anticoagulant effect; the mechanism is not well established.
What to do
Advise patients to avoid anamu during argatroban therapy. If used, monitor aPTT and watch for bleeding.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Argatroban
- Argatroban + Defibrotide Contraindicated
- Argatroban + Ketorolac Contraindicated
- Argatroban + Mifepristone Contraindicated
- Abciximab + Argatroban Major
- Acalabrutinib + Argatroban Major
- Acetylsalicylic acid + Argatroban Major
Frequently asked questions
Can I take Anamu with Argatroban?
MediHelp rates the interaction as moderate. Anamu and Argatroban can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Anamu (Petiveria alliacea) has been reported to have antiplatelet or anticoagulant-like activity in laboratory studies. Combined use with argatroban could theoretically raise bleeding risk, but clinical data are scarce.
How serious is the interaction between Anamu and Argatroban?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid anamu during argatroban therapy. If used, monitor aPTT and watch for bleeding.
What other medicines interact with Argatroban?
MediHelp also lists interactions of Argatroban with, for example, Defibrotide, Ketorolac, Mifepristone. The full list is on the Argatroban page.
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