Drug interactions
Anifrolumab + Measles mumps and rubella vaccine
Severity: Moderate
Anifrolumab and Measles mumps and rubella vaccine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Anifrolumab blocks type I interferon signaling, which is important for antiviral immunity. Live MMR vaccine may carry a risk of vaccine-strain infection and the response is uncertain.
What this interaction means in plain words
Anifrolumab and Measles mumps and rubella vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Anifrolumab belongs to Miscellaneous; Measles mumps and rubella vaccine belongs to Miscellaneous.
Why it happens
Type I interferon receptor blockade reduces antiviral immune responses to replicating attenuated virus.
What to do
Update live vaccines before starting anifrolumab; avoid live vaccines during treatment.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Anifrolumab and Measles mumps and rubella vaccine, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Measles mumps and rubella vaccine
- Adalimumab + Measles mumps and rubella vaccine Contraindicated
- Anakinra + Measles mumps and rubella vaccine Contraindicated
- Antithymocyte globulin equine + Measles mumps and rubella vaccine Contraindicated
- Antithymocyte globulin rabbit + Measles mumps and rubella vaccine Contraindicated
- Azathioprine + Measles mumps and rubella vaccine Contraindicated
- Basiliximab + Measles mumps and rubella vaccine Contraindicated
Other interactions of Anifrolumab
- Anifrolumab + Warfarin Minor
Frequently asked questions
Can I take Anifrolumab with Measles mumps and rubella vaccine?
MediHelp rates the interaction as moderate. Anifrolumab and Measles mumps and rubella vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Anifrolumab blocks type I interferon signaling, which is important for antiviral immunity. Live MMR vaccine may carry a risk of vaccine-strain infection and the response is uncertain.
How serious is the interaction between Anifrolumab and Measles mumps and rubella vaccine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Update live vaccines before starting anifrolumab; avoid live vaccines during treatment.
What other medicines interact with Measles mumps and rubella vaccine?
MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Anakinra, Antithymocyte globulin equine. The full list is on the Measles mumps and rubella vaccine page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
