Drug interactions
Anthrax vaccine adsorbed + Certolizumab pegol
Severity: Minor
Anthrax vaccine adsorbed and Certolizumab pegol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Immunosuppressive therapy such as TNF blockade may reduce the immune response to anthrax vaccine. Protection may be lower than in immunocompetent people.
What this interaction means in plain words
Anthrax vaccine adsorbed and Certolizumab pegol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Pharmacodynamic antagonism: TNF inhibition dampens vaccine-induced antibody responses.
What to do
Give the vaccine, ideally before starting certolizumab when feasible, and consider confirming immune response if exposure risk is high.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Certolizumab pegol
- Adenovirus types 4 and 7 live + Certolizumab pegol Contraindicated
- Bcg intravesical live + Certolizumab pegol Contraindicated
- Bcg vaccine live + Certolizumab pegol Contraindicated
- Certolizumab pegol + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Certolizumab pegol + Measles mumps and rubella vaccine Contraindicated
- Certolizumab pegol + Measles mumps and rubella vaccine live Contraindicated
Frequently asked questions
Can I take Anthrax vaccine adsorbed with Certolizumab pegol?
MediHelp rates the interaction as minor. Anthrax vaccine adsorbed and Certolizumab pegol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Immunosuppressive therapy such as TNF blockade may reduce the immune response to anthrax vaccine. Protection may be lower than in immunocompetent people.
How serious is the interaction between Anthrax vaccine adsorbed and Certolizumab pegol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give the vaccine, ideally before starting certolizumab when feasible, and consider confirming immune response if exposure risk is high.
What other medicines interact with Certolizumab pegol?
MediHelp also lists interactions of Certolizumab pegol with, for example, Adenovirus types 4 and 7 live, Bcg intravesical live, Bcg vaccine live. The full list is on the Certolizumab pegol page.
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