Drug reference
certolizumab pegol
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Musculoskeletal (TNF-alpha Inhibitors)
Mechanism of action
Recombinant humanized antihuman TNF-alpha neutralizing antibody Binds to human TNFα with a KD of 90pM; TNF-alpha is a key pro-inflammatory cytokine with a central role in inflammatory processes
Common side effects
- URI
- Nasopharyngitis
- Arthralgia
- Headache
- Serious infections
Contraindications
- History of hypersensitivity reaction to certolizumab pegol or to any of the excipients; reactions have included angioedema, anaphylactoid reaction, serum sickness, and urticaria
Known interactions (2)
- certolizumab pegol + measles mumps and rubella vaccine Contraindicated
- certolizumab pegol + upadacitinib Major
Related conditions
Frequently asked questions
What drug class is certolizumab pegol?
certolizumab pegol belongs to: Musculoskeletal.
How does certolizumab pegol work?
Recombinant humanized antihuman TNF-alpha neutralizing antibody Binds to human TNFα with a KD of 90pM; TNF-alpha is a key pro-inflammatory cytokine with a central role in inflammatory processes
What are the common side effects of certolizumab pegol?
URI, Nasopharyngitis, Arthralgia, Headache, Serious infections
Which drugs interact with certolizumab pegol?
measles mumps and rubella vaccine, upadacitinib
Full monographs, dosing and an interaction checker in the MediHelp app
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