Drug interactions
Anthrax vaccine + Azathioprine
Severity: Moderate
Anthrax vaccine and Azathioprine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Anthrax vaccine is non-live, so no vaccine infection is expected. Azathioprine may lower the antibody response and reduce protection.
What this interaction means in plain words
Anthrax vaccine and Azathioprine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Azathioprine suppresses lymphocyte proliferation, reducing antibody production.
What to do
Vaccinate when indicated, as the vaccine is not live. Where possible vaccinate before starting azathioprine, and consider checking antibody response in high-risk exposure.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Azathioprine
- Adenovirus types 4 and 7 live + Azathioprine Contraindicated
- Azathioprine + Bcg vaccine live Contraindicated
- Azathioprine + Febuxostat Contraindicated
- Azathioprine + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Azathioprine + Measles mumps and rubella vaccine Contraindicated
- Azathioprine + Measles mumps and rubella vaccine live Contraindicated
Frequently asked questions
Can I take Anthrax vaccine with Azathioprine?
MediHelp rates the interaction as moderate. Anthrax vaccine and Azathioprine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Anthrax vaccine is non-live, so no vaccine infection is expected. Azathioprine may lower the antibody response and reduce protection.
How serious is the interaction between Anthrax vaccine and Azathioprine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate when indicated, as the vaccine is not live. Where possible vaccinate before starting azathioprine, and consider checking antibody response in high-risk exposure.
What other medicines interact with Azathioprine?
MediHelp also lists interactions of Azathioprine with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Febuxostat. The full list is on the Azathioprine page.
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